Game Preview 49ers vs Bills

To start off, this 49ers record is misleading due to injuries, when healthy San Francisco can compete with any team in the league. That being said they’re still missing pieces but getting Richard Sherman back last week and getting Debo and Mosert on the offensive side was huge. In this battle I believe we are going to see a big running game against the Bills, applying motion and a running back by committee featuring Mosert, Coleman, and Wilson. With Brandon Aiyuk being back this week you can expect the dynamic duo of Deebo and Brandon back on the field. With the Bills being the 10th ranked offense behind Josh Allen and Stefon Diggs, you can expect a battle between Sherman and Diggs.

My keys to this game is the defense getting pressure on the Bills, forcing Josh Allen out of the pocket, and letting our Linebackers make plays. Offensively we need get out running game established and get the ball out quickly to the YAC squad. My player to keep an eye out for is Mosert, expect him to have a solid game.

Predicted score: 49ers 24-Bills 21

SF -1.5